Metabolomics is a technique for comprehensively measuring metabolites (the metabolome) in living organisms. The metabolome is equivalent to the furthest stage downstream of the process of expressing genetic information. Accordingly, it can be considered as directly reflecting the phenotype of the organism. Because of this, applications of metabolomics are anticipated in a variety of fields including drug discovery, functional foods, and metabolic engineering.

The Shim-pack Mix-HILIC chromatography column for hydrophilic interactions enables separation of important amino acids in organisms as well as nucleobases, nucleosides, nucleotides, coenzymes, and organic acids via characteristic hydrophilic interactions and ionic interactions. Accordingly, it is suitable for the simultaneous monitoring of hydrophilic metabolites with a variety of physicochemical properties.